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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RCC1
All Species:
21.21
Human Site:
S336
Identified Species:
38.89
UniProt:
P18754
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18754
NP_001041659.1
421
44969
S336
G
E
G
A
E
E
K
S
I
P
T
L
I
S
R
Chimpanzee
Pan troglodytes
XP_001152659
421
44920
S336
G
E
G
A
E
E
K
S
I
P
T
L
I
S
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544458
630
67681
S545
G
E
G
A
E
E
K
S
I
P
T
L
I
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE37
421
44912
S336
G
E
G
A
E
E
K
S
I
P
T
L
I
S
R
Rat
Rattus norvegicus
NP_001121661
421
45093
S336
G
E
G
A
E
E
K
S
I
P
T
L
I
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_427366
194
21051
M111
S
G
N
D
H
L
V
M
L
T
V
D
G
D
L
Frog
Xenopus laevis
P25183
424
45052
S341
G
E
N
A
E
E
Q
S
E
P
T
P
I
P
D
Zebra Danio
Brachydanio rerio
Q6NYE2
495
54133
D399
M
Y
P
K
A
V
Q
D
L
C
G
W
K
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25171
547
58832
E335
G
D
V
K
D
V
V
E
K
P
T
I
V
K
K
Honey Bee
Apis mellifera
XP_394158
439
46956
L349
N
C
L
D
A
K
E
L
T
L
V
P
N
L
S
Nematode Worm
Caenorhab. elegans
Q18211
569
61466
A465
M
G
K
N
T
D
N
A
L
G
L
G
N
W
T
Sea Urchin
Strong. purpuratus
XP_001191815
424
45249
P341
D
C
E
E
S
H
I
P
T
L
I
S
A
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21827
482
52995
P385
H
G
K
A
R
A
V
P
L
P
T
K
L
N
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
64.7
N.A.
93.8
93.3
N.A.
N.A.
37
75.9
22.2
N.A.
29
45.5
29.5
52.8
Protein Similarity:
100
99.7
N.A.
65.8
N.A.
96.9
96.6
N.A.
N.A.
42
85.6
40
N.A.
43.6
63
42.5
70.7
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
0
60
6.6
N.A.
20
0
0
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
6.6
66.6
20
N.A.
53.3
13.3
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
54
16
8
0
8
0
0
0
0
8
0
0
% A
% Cys:
0
16
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
8
0
16
8
8
0
8
0
0
0
8
0
8
8
% D
% Glu:
0
47
8
8
47
47
8
8
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
54
24
39
0
0
0
0
0
0
8
8
8
8
0
0
% G
% His:
8
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
39
0
8
8
47
8
0
% I
% Lys:
0
0
16
16
0
8
39
0
8
0
0
8
8
8
16
% K
% Leu:
0
0
8
0
0
8
0
8
31
16
8
39
8
8
8
% L
% Met:
16
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
0
16
8
0
0
8
0
0
0
0
0
16
8
8
% N
% Pro:
0
0
8
0
0
0
0
16
0
62
0
16
0
8
0
% P
% Gln:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
47
% R
% Ser:
8
0
0
0
8
0
0
47
0
0
0
8
0
39
8
% S
% Thr:
0
0
0
0
8
0
0
0
16
8
62
0
0
0
8
% T
% Val:
0
0
8
0
0
16
24
0
0
0
16
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _